Born and raised in Clayton, Missouri, Dr. Drazen majored in applied physics at Tuft University and graduated from Harvard Medical School in 1972. After serving his medical internship at Peter Bent Brigham Hospital in Boston, he joined the pulmonary divisions of the Harvard hospitals. He served as chief of Pulmonary Medicine at the Beth Israel Hospital, chief of the combined Pulmonary Divisions of the Beth Israel and Brigham and Women’s Hospitals, and then as chief of Pulmonary Medicine at Brigham and Women’s Hospital. Through his research, Dr. Drazen defined the role of novel endogenous chemical agents in asthma, leading to four new licensed pharmaceuticals for asthma with millions of people on treatment worldwide. In 2000, he assumed the post of editor-in-chief of the New England Journal of Medicine. During his tenure, the Journal has published major papers advancing the science of medicine including the first descriptions of SARS, timely coverage of the Ebola epidemic and Zika virus, and modifications in the treatment of cancer, heart disease and lung disease. It has also been at the forefront of the international effort to register all clinical trials. The Journal, which has over a million readers every week, has the highest impact factor of any journal publishing original research.